01/01/2021 Biology
DOI: 10.1051/bioconf/20214102005 SemanticScholar ID: 245430401

Copy number alterations in cancer: detection and precision medicine

Publication Summary

Copy number alterations (CNAs) are genomic alterations where some regions exhibit more or less copy number than the normal two copies. In this talk, I will describe two ideas: (1) how CNAs are estimated from data generated by next generation sequencing (NGS) and what steps are required to make the data interpretable, (2) how the CNA can be utilised for precision medicine in terms of prediction of tumour subtypes and prediction of cancer patients’ survival. If time permits, I will also discuss how to estimate genomic markers from CNA profile across cancer patients.

CAER Authors

Avatar Image for Arief Gusnanto

Dr. Arief Gusnanto

University of Leeds

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